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help us discover
a new generation
of medicines

drug hunting is in our DNA

We are physicians, biologists, chemists, data scientists and drug developers – every one of us laser focused on transforming the lives of patients with innovative medicines.

If you thrive in a fun, fast-paced and highly collaborative environment, you’ll love working with us at Empirico. We offer competitive salaries and benefits, meaningful stock ownership and the opportunity to live and work in two of America’s greatest biotech cities – San Diego, California and Madison, Wisconsin.

We’re always looking for talented people who share our passion for improving patients’ lives. If you feel driven to contribute but don’t see an open position that fits your specific background or skills, let us know at careers@empiricotx.com.

open positions

  • Associate Director/Director - Development Program Management

    San Diego, CA; Madison, WI; or Remote
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    Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a talented scientist to help advance our growing pipeline. This position offers a unique opportunity to participate and support multiple projects across different stages of preclinical development in multiple therapeutic areas. You will work closely with other scientists that have a passion for finding novel approaches toward the treatment and prevention of disease.

    Responsibilities:

    You will be accountable for the cross-functional planning and execution of one or more development programs, including definition of the operational strategy, management of the timelines, risk assessment and mitigation, and budget. You will be expected to –

    • Create and maintain a cross-function development plan, timeline and budget for each program and ensuring progress vs. plan
    • Facilitate effective, science-based business decisions including the generation of multiple development scenarios/options as needed, highlighting interdependencies and downstream impacts (including but not limited to timelines and budget) of strategic decisions
    • Proactively identify risks and ensure mitigation plans are implemented
    • Communicate to leadership, team members and other stakeholders in a transparent and timely manner
    • Alongside the development leadership, work to foster a high performing team and monitor the health and operating efficiency of the team
    • Lead the creation of team norms and operating principles with a focus on cross-functional input and accountability

    Requirements:

    • BS/MS degrees in a scientific discipline, in combination with extensive experience in multiple drug development programs at various stages (at least through Phase 2)
    • Demonstrated competency in early and/or late phase drug development with solid understanding of the drug development pathway
    • Ability to facilitate and contribute to strategic discussions
    • Leadership skills including situational leadership, ability to lead a team of experts and influence without authority
    • Demonstrated ability to lead matrix teams; know how to work at the strategic level with the development leadership team; have the ability to delve deeper in order to resolve issues and challenges
    • Strong communication skills with an ability to integrate and succinctly summarize the various parts of a project and effectively tailor messages to the audience, including senior leadership
    • Ability to lead the development of critical path analyses and scenario planning
    • Ability to manage difficult stakeholder situations and resolve complex problems
    • Proficiency with Word, PowerPoint, Excel, SharePoint, Smartsheet, and other project management tools
    • Applicants must have authorization to work in the U.S.

    The estimated base salary range for this role is $120,000 to $210,000. Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. We offer a wide range of benefits including a retirement savings plan (with company match), paid vacation, holidays, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

    About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform™ for genetically-validated target discovery and the siRCH™ platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.

    We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

    To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

    APPLY NOW
  • Senior Data Scientist - Bioinformatics

    San Diego, CA or Remote
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    Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a talented data scientist experienced in human genetics and bioinformatics who is interested in applying these skills towards interpreting large scale human genetics data for the purpose of therapeutic target discovery. This is an excellent opportunity for a highly-motivated, creative data scientist to be a vital member of a team of experts dedicated to identifying new therapeutic targets and translating those insights into drug discovery and development programs.

    Responsibilities:

    Your responsibilities will primarily consist of performing analyses and building robust computational pipelines and tools critical to Empirico’s target discovery efforts. You will be expected to –

    • Collaborate closely with a multidisciplinary team consisting of human geneticists, biologists, bioinformatics scientists and software engineers, and use your data analysis skills to gain insights from massive genetic datasets
    • Work independently and as part of a team to complete projects related to:
      • Deploying robust, scalable data analysis pipelines, software tools, and web applications to support target discovery – including innovative methods to analyze genetic and phenotypic data
      • Implementing cutting-edge analytical methods and algorithms (both internally-developed and those described in the literature)
      • Integrating, analyzing and visualizing large, complex data sets to extract information useful to our target discovery efforts
    • Perform focused genetic analyses to gain insights into novel target biology and clearly communicate these analyses to Empirico colleagues
    • Perform analyses to address critical platform/application QC

    Requirements:

    • This position requires a MS or PhD in bioinformatics or a related discipline (e.g. computer science)
    • Core background MUST be in data science or bioinformatics; this position is NOT for scientists with a primarily wet-lab background
    • Strong skills in at least one programming language (preferably Python)
    • Familiarity with Linux command-line based tools and bash scripting
    • Experience using HPC/cloud computing environments (AWS, Azure, GCP)
    • Demonstrated experience processing, analyzing, and visualizing genetic datasets to make scientific insights
    • A strong understanding of applied statistical methods and the principles of statistical genetics
    • Experience working with RNA-seq (or scRNA-seq), GWAS data, and other omics data types a plus
    • Experience working with UK Biobank data or other large-scale biomedical databases a plus
    • Full stack development experience a plus, but not expected
    • Comfortable with version control systems such as Git
    • Demonstrated ability for writing readable, testable, and SOLID code
    • Applicants must have authorization to work in the U.S.

    The estimated base salary range for this role is $80,000 to $150,000.  Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills.  We offer a wide range of benefits including a retirement savings plan (with company match), paid vacation, holidays, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

    About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform™ for genetically-validated target discovery and the siRCH™ platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.

    We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

    To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

    APPLY NOW
  • Senior Scientist - Target Biology

    San Diego, CA
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    Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a talented scientist to support our neuroscience drug discovery programs.

    Responsibilities:

    Your responsibilities will include leading in vitro pharmacology efforts that will elucidate novel drug target mechanisms and establish causal relationships between drug target modulation and neurological diseases. The ideal candidate will have extensive experience in developing and utilizing in vitro models of neurodegenerative and other neurological diseases. You will be expected to –

    • Design and conduct rigorous experiments, including cell-based and biochemical assays, to explore novel drug targets, aimed at yielding definitive yes/no answers
    • Maintain a highly organized, detail-oriented, and data-driven approach to research, ensuring accurate problem-solving and experiment execution
    • Utilize exceptional data analysis and presentation skills to effectively communicate complex research findings
    • Occasionally partner with Contract Research Organizations (CROs) to develop reagents or perform assays, contributing to project advancements
    • Act as a team player, committed to fostering a collaborative, transparent, and productive work environment

    Requirements:

    • PhD in cell biology, molecular biology, physiology, biochemistry or related field with at least 3 years of relevant experience or a Master’s Degree with at least 10 years of relevant experience
    • Proven extensive hands-on expertise in the culture and manipulation of primary neurons and other central nervous system (CNS) cell types
    • Experience developing cell-based models of neurodegeneration is a plus
    • Experience with in vitro delivery of oligonucleotides is a plus
    • Demonstrated capability to mentor or supervise other technical staff
    • Applicants must have authorization to work in the U.S.

    The estimated base salary range for this role is $110,000 to $150,000. Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. We offer a wide range of benefits including a retirement savings plan (with company match), paid vacation, holidays, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

    About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform™ for genetically-validated target discovery and the siRCH™ platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.

    We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

    To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

    APPLY NOW
  • Quality Associate/Manager

    Madison, WI
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    Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a talented and experienced Quality professional who will be a key member of the development team. This is an excellent opportunity for an organized and highly-motivated individual who will operate across QA and QC functions.

    Responsibilities:

    You will use knowledge and experience in drug development within the pharmaceutical industry to implement phase-appropriate quality documentation and practices. You will be expected to –

    • Provide Quality oversight in collaboration with internal and external stakeholders to ensure that operations are manufactured, tested, stored and distributed according to Good Manufacturing Practices (cGMP), Good Clinical Practices (GCP) and other applicable regulations
    • Oversee Empirico’s quality management system (QMS)
    • Author, review, and approve documents such as Standard Operating Procedures (SOPs), training materials, analytical methods, protocols, and other documents
    • Provide Quality review of all documentation required for regulatory applications
    • Collaborate with internal and external stakeholders including senior leadership
    • Implement strategies to improve Quality within Empirico
    • Communicate with and host meetings to train colleagues about ways to improve Quality
    • Ensure compliance with phase-appropriate ICH guidelines and GxP regulations
    • Provide Quality support for Bioanalytical, DMPK, Manufacturing, Project Management, Toxicology, Clinical Operations, etc.
    • Participate in meetings with vendors and other external organizations as the Quality representative

    Requirements:

    • This position requires a Bachelor’s degree in a scientific field
    • At least 2 years of relevant Quality Assurance or Quality Control experience, or equivalent, in the pharmaceutical or related industry
    • Proficiency in the use of Excel, PowerPoint, Word, and project management tools
    • Previous experience with GxP quality management systems within the pharmaceutical industry
    • Previous experience with GxP documentation
    • Excellent written, verbal and interpersonal communication skills with the ability to effectively interact with diverse operational teams, both within and outside the company, to establish credibility with project partners (such as CROs, CMOs and internal stakeholders).
    • Experience working in a regulatory environment
    • Exceptional organizational and time management skills and the ability to multi-task
    • A detail-oriented self-starter who endeavors to anticipate and resolve problems and seeks opportunities to grow their role and responsibilities at Empirico
    • Ability for minimal business travel (< 10%)
    • Applicants must have authorization to work in the U.S.

    The estimated base salary range for this role is $70,000 to $120,000. Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. We offer a wide range of benefits including a retirement savings plan (with company match), paid vacation, holidays, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

    About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform™ for genetically-validated target discovery and the siRCH™ platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.

    We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

    To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

    APPLY NOW
  • Scientific/Medical Writer

    Madison, WI
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    Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a motivated Scientific/Medical Writer who collaborates with members of cross-functional teams to contribute to and prepare high-quality pre-clinical study reports and required regulatory documents within agreed-upon timelines. This is an excellent opportunity for a highly motivated, detail-oriented, and organized individual to be a vital member of a team of experts dedicated to identifying new disease targets and translating those insights into therapeutic programs.

    Responsibilities:

    Your responsibilities will include creating scientific and medical documents in various formats, carefully reviewing processed data, planning and organizing, establishing effective working interactions with scientific and project management teams, and efficiently producing high-quality deliverables. You will be expected to –

    • Work with program leaders and scientists to generate new and revise existing pre-clinical study reports and other scientific/medical communications
    • Draft and edit documents obtained from both internal and external pre-clinical studies to aggregate and report safety and efficacy information
    • Manage document reviews and adjudication of comments on procedures and associated forms and templates by liaising with program leaders and scientists
    • Act as quality control specialist in reviewing processed data and ensuring accuracy in data reporting
    • Adhere to company procedures/practices and industry standards
    • Track timelines and status of document development and review

    Requirements:

    • Minimum BS/BA in a scientific or technical discipline (advanced degree preferred)
    • 3+ years of related experience
    • Experience required in scientific writing with a strong preference for those with similar work experience in the biopharmaceutical industry
    • Expert MS Office skills with a special focus on word processing, tables, spreadsheets, presentations, graphics, and templates
    • Hands-on experience in using GraphPad Prism and Microsoft SharePoint
    • Ability to critically analyze and synthesize complex scientific data and information
    • Excellent communication skills, both oral and written
    • Extensive experience in applying writing style guidelines and standards
    • Applicants must have authorization to work in the U.S.

    The estimated base salary range for this role is $70,000 to $100,000. Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. We offer a wide range of benefits including a retirement savings plan (with company match), paid vacation, holidays, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

    About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform™ for genetically-validated target discovery and the siRCH™ platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.

    We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

    To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

    APPLY NOW
  • Scientist/Senior Scientist - Oligonucleotide Chemistry

    Madison, WI
    READ MORE READ LESS

    Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a talented chemist with experience in solid-phase oligonucleotide synthesis and analytics. This is an excellent opportunity for a highly-motivated, creative scientist to be a vital member of our team.

    Responsibilities:

    • Perform solid phase synthesis, purification, and characterization of oligonucleotides and oligonucleotide conjugates
    • Analyze, interpret, and communicate synthetic and analytical results
    • Present results at group meetings to senior staff
    • Troubleshoot and optimize current procedures
    • Ability to multitask and work on several projects simultaneously

    Requirements:

    • This position requires a PhD in Organic Chemistry, or a Master’s degree in combination with at least one year of experience in a GMP lab environment
    • Experience with High-Performance Liquid Chromatography
    • Desire to work in a fast-paced and dynamic environment
    • 1-7 years of relevant work experience, preferably in solid phase synthesis
    • Experience with RPIP-HPLC, AEX-HPLC, UV, NMR, LCMS, MALDI, and HRMS is highly desired
    • Analytical or purification method development experience using RPIP-HPLC and AEX-HPLC
    • Applicants must have authorization to work in the U.S.

    The estimated base salary range for this role is $75,000 to $140,000. Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. We offer a wide range of benefits including a retirement savings plan (with company match), paid vacation, holidays, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

    About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform™ for genetically-validated target discovery and the siRCH™ platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.

    We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

    To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

    APPLY NOW
  • Associate Scientist/Scientist - Oligonucleotide Chemistry

    Madison, WI
    READ MORE READ LESS

    Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a talented chemist with an interest in solid-phase oligonucleotide synthesis and analytics. This is an excellent opportunity for a highly-motivated, creative scientist to be a vital member of our team.

    Responsibilities:

    • Perform solid phase synthesis, purification, and characterization of oligonucleotides and oligonucleotide conjugates
    • Analyze, interpret, and communicate synthetic and analytical results
    • Present results at group meetings to senior staff
    • Troubleshoot and optimize current procedures
    • Ability to multitask and work on several projects simultaneously
    • Maintain inventory of reagents and consumables

    Requirements:

    • This position requires a Bachelor’s degree in Chemistry or Biochemistry with understanding of organic and analytical chemistry
    • Experience working in a chemistry lab
    • Experience with High-Performance Liquid Chromatography
    • Desire to work in a fast-paced and dynamic environment
    • 1-7 years of relevant work experience, preferably in solid phase synthesis
    • Experience with RPIP-HPLC, AEX-HPLC, UV, NMR, LCMS, MALDI, and HRMS is highly desired
    • Analytical or purification method development experience using RPIP-HPLC and AEX-HPLC
    • Applicants must have authorization to work in the U.S.

    The estimated base salary range for this role is $50,000 to $120,000. Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. We offer a wide range of benefits including a retirement savings plan (with company match), paid vacation, holidays, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

    About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform™ for genetically-validated target discovery and the siRCH™ platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.

    We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

    To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

    APPLY NOW
  • Scientist - Drug Discovery

    Madison, WI
    READ MORE READ LESS

    Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a talented scientist to help advance our growing pipeline. This position offers a unique opportunity to participate and support multiple projects across different stages of preclinical development in multiple therapeutic areas. You will work closely with other scientists that have a passion for finding novel approaches toward the treatment and prevention of disease.

    Responsibilities:

    Your responsibilities will include establishing and performing a wide variety of biochemical and molecular biological assays intended to provide key study readouts. The ideal candidate will have extensive experience in both nucleic acid-based and protein-based assay systems. This candidate will be highly organized and enjoy working in a team environment. You will be expected to –

    • Work with other scientists to execute analytical aspects of study protocols, such as design and implementation of specialized pharmacokinetics and biomarker assays (immunoassays, quantitative PCR, stem-loop PCR)
    • Recognize analytical and experimental design challenges and actively provide insight into solutions
    • Analyze data utilizing statistical methods, data quality testing and result verification, and graphical representation of data for reports and presentations.
    • Write SOPs for assay procedures and general lab procedures
    • Maintain a high level of productivity in the lab and perform critical experiments

    Requirements:

    • PhD in biochemistry, molecular biology, pharmacology, or a Master’s Degree in combination with at least 5 years of experience, or Bachelor’s Degree in combination with at least 10 years of experience, in biochemistry, immunology, pharmacology, or related fields
    • Advanced knowledge of qPCR, immunological techniques (immunoassays, Western blot, flow cytometry, etc.) primary cell culture, tissue processing, as well as standard molecular biology and biochemical techniques
    • Desire to work in a fast-paced and dynamic environment
    • Applicants must have authorization to work in the U.S.

    The estimated base salary range for this role is $75,000 to $120,000. Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. We offer a wide range of benefits including a retirement savings plan (with company match), paid vacation, holidays, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

    About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform™ for genetically-validated target discovery and the siRCH™ platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.

    We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

    To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

    APPLY NOW
  • Laboratory Assistant - Chemistry (Part-Time, Temporary)

    Madison, WI
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    Position Description: Empirico, a biotechnology company that combines unmatched expertise in human genetics-driven target discovery with world-class capabilities in siRNA drug discovery, is looking for a laboratory assistant to help with routine chemistry laboratory operations. The successful applicant for this part-time, temporary position is expected to work approximately 10-15 hours per week, with the potential for additional hours depending on availability and need. This is an excellent opportunity to gain hands-on experience working at a highly-innovative biotechnology company together with experienced scientists that have a passion for finding novel approaches toward the treatment and prevention of disease.

    Responsibilities:

    • Ordering and receiving of reagents and supplies
    • Laboratory inventory management
    • General laboratory housekeeping including dishwashing
    • Solution and buffer preparation
    • Performing laboratory procedures (for which training will be provided) using ultraviolet-visible spectroscopy, high-performance liquid chromatography, and mass spectrometry

    Requirements:

    • Currently enrolled in a post-secondary institution
    • Enrolled in chemistry laboratory classes (experience performing routine laboratory assays and reagent preparation is a plus)
    • Applicants must have authorization to work in the U.S.

    The estimated hourly rate for this role is $12.00 to $18.00 per hour. Individual compensation decisions will be based on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills.

    About Empirico: Empirico is a biotechnology company focused on the discovery and development of novel medicines which mimic the effects of naturally-occurring genetic variants that confer favorable effects on health and disease. Empirico’s two foundational technology platforms – the Precision Insights Platform™ for genetically-validated target discovery and the siRCH™ platform for the discovery and development of siRNA medicines – are used separately and in tandem to enable Empirico and our collaborators from the discovery and validation of novel targets to clinically-viable therapeutics. Empirico’s exceptional internal capabilities, augmented by those of its partners, are driving the advancement of a growing and differentiated pipeline of wholly-owned and partnered programs. Empirico is headquartered in San Diego, CA with a major second site in Madison, WI.

    We’re striving to build a strong culture of inclusivity, transparency and collaboration at Empirico, where our diverse and equitable workforce is empowered to contribute to our mission. We always seek the best candidate for the position and encourage you to apply even if your experience or qualifications don’t match up exactly with the job description. Empirico is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

    To All Agencies: Please do not contact any employee of Empirico about this position. All resumes submitted by agencies to any employee of Empirico via-email or in any form and by any method will be deemed the sole property of Empirico, unless such agencies were engaged by Empirico for this position and a valid agreement is in place.

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    We’re always looking for talented people who share our passion for improving patients’ lives. If you feel driven to contribute but don’t see an open position that fits your specific background and skills, let us know at careers@empiricotx.com.

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